Effect of sucralfate on aspirin induced mucosal injury and impaired haemostasis in humans.
نویسندگان
چکیده
منابع مشابه
Effect of sucralfate on aspirin induced mucosal injury and impaired haemostasis in humans.
BACKGROUND Sucralfate does not have potent anti-ulcerogenic actions in users of non-steroidal anti-inflammatory drugs (NSAIDs). However, sucralfate may influence intragastric haemostasis favourably. AIM To investigate separately the effects of sucralfate on acute gastric and duodenal injury and on changes in intragastric bleeding induced by aspirin. METHOD On three occasions, 24 healthy vol...
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15 صفحه اولEffect of sucralfate on gastric mucosal blood flow in rats.
Sucralfate possesses site protective and cytoprotective actions and heals ulcers effectively, but its effect on gastric mucosal blood flow is unknown. Using an ex vivo gastric chamber preparation, we studied the effect of sucralfate on gastric mucosal blood flow in rats by laser doppler flowmetry. Under both fasting and fed states, measurements of gastric mucosal blood flow and damage were made...
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ژورنال
عنوان ژورنال: Gut
سال: 1997
ISSN: 0017-5749
DOI: 10.1136/gut.41.1.19